Take your dose of oral Minoxidil at the same time each day, once a day. You may take Minoxidil with or without food, but you may want to try taking it with food if you notice stomach upset after your dose. If you miss a dose and are only off by a few hours, you may go ahead and take your missed dose. However, if you missed a dose and it has been more than a few hours skip your dose and continue on like usual the next day.